Puggles have several drawbacks including health issues such as breathing difficulties, heat sensitivity, eye problems, joint conditions like hip dysplasia, skin and ear infections, and reverse sneezing due to their Pug heritage. They are energetic and sometimes stubborn, requiring consistent training and ample exercise. Puggles can also be prone to obesity and tend to howl, especially when left alone, which may lead to separation anxiety and nuisance barking.