Chronic treatment-resistant demodicosis in dogs is a complex skin condition caused by microscopic mites from the Demodex species. These cigar-shaped mites inhabit the hair follicles of nearly all dogs. Although typically harmless, an imbalance in the immune system can cause these mites to multiply rapidly, leading to irritation, inflammation, and the development of demodicosis. This condition can become persistent and difficult to treat, especially when the immune system is compromised or other health issues are present.
Demodicosis can appear at various life stages of a dog. Juvenile onset typically manifests in puppies aged 3 to 18 months, either locally or generally, often linked to genetic predispositions affecting the immune response. Most juvenile cases resolve as a puppy matures, provided they remain healthy and free from other infections.
Adult onset demodicosis usually emerges around four years of age or older, often as a generalised and more severe form. It is commonly caused by underlying systemic disorders such as cancer or hormonal imbalances, which suppress the immune system and allow mite populations to flourish.
Dogs with demodicosis display hair loss in patches, inflamed and reddened skin, often on the face, head, and feet. While these areas may not itch, severe generalised demodicosis causes lesions, sores, skin thickening, and secondary bacterial or yeast infections that can result in bleeding and pain, occasionally spreading to the ears and other parts of the body.
To diagnose this condition, a vet will review the dog's medical history and perform a physical examination focusing on affected skin areas. Diagnosis involves plucking hairs to inspect under a microscope for mites. If large numbers of mites are found, specialised tests such as blood tests, CT scans, or ultrasounds may be conducted to identify any underlying systemic health issues contributing to the condition.
Management usually involves outpatient care with frequent veterinary visits to monitor recovery and prevent recurrence. Treatment-resistant cases require an aggressive approach. Vets may perform skin cultures to rule out resistant bacterial infections like Methicillin-resistant Staphylococcus intermedius. Long-term therapy aimed at both mite eradication and addressing underlying health concerns is essential.
Prolonged treatment periods are common, sometimes lasting several months, and success is not always guaranteed. When licensed treatments fail, vets may recommend non-licensed medications and supportive care tailored to the individual dog's needs, always ensuring responsible use and monitoring to reduce side effects.
The outlook for dogs with localised or generalised demodicosis is generally favourable, particularly when identified early and treated appropriately. However, chronic treatment-resistant demodicosis requires regular veterinary monitoring and adjustment of treatment plans. Addressing underlying systemic illnesses is crucial to improving a dog’s chances of recovery and maintaining their quality of life.
Owners are encouraged to maintain routine veterinary check-ups and observe any changes in their dog's skin or behaviour. Early veterinary intervention offers the best chance for successful treatment. Responsible breeding practices to reduce genetic predisposition to immune deficiencies can help prevent juvenile demodicosis. When acquiring puppies, finding puppies from reputable breeders committed to health testing is vital.