Exocrine pancreatic insufficiency (EPI) in dogs is a serious digestive disorder where the pancreas cannot produce the enzymes needed to break down food properly. This results in nutrients passing through undigested and can lead to severe weight loss despite a healthy appetite. Known as maldigestion syndrome, EPI requires lifelong management to ensure your dog maintains good health and quality of life.
EPI occurs when the pancreas fails to produce sufficient digestive enzymes, essential for breaking down fats, proteins, vitamins, and carbohydrates. Without these enzymes, nutrients cannot be absorbed properly, leading to symptoms such as weight loss, prolific pale diarrhoea with a strong odour, and malnutrition. Veterinarians diagnose EPI through blood tests and stool enzyme analysis, and early detection is key to successful management.
After diagnosis, dogs often require hospitalisation for intensive care, including enzyme supplementation and weight stabilisation. Once stable, treatment continues at home with a carefully planned diet and enzyme therapy overseen by your vet.
Feeding your dog multiple small meals throughout the day (typically 3-4) helps reduce digestive strain and optimises enzyme effectiveness. With time and improvement, meal frequency may be reduced to twice daily to fit your routine. Always administer pancreatic enzyme supplements as directed—either sprinkled on food or given as pills shortly before meals, depending on your vet's recommendation.
Your dog's diet should be low in fat (around 10-15% on a dry matter basis, sometimes lower depending on tolerance) and fibre, as excessive fat and fibre can decrease enzyme efficiency and exacerbate maldigestion. High-quality protein such as lean chicken (skin removed), beef, or pork is essential for rebuilding and maintaining muscle mass. Carbohydrates should come from easily digestible sources, with minimal starch and sugars, as starch may stress the pancreas further.
Commercial diets often do not meet these specialised needs, so vets might recommend prescription diets formulated for EPI or advise on home-cooked meals tailored to your dog's condition. Labrador retriever puppies or other breeds can be prone to such conditions, so if you're considering getting a dog, working with reputable breeders helps ensure better genetic health.
Dogs with EPI frequently suffer deficiencies in vitamin B12 (cobalamin) due to malabsorption linked with abnormal intestinal bacterial growth. This deficiency can also reduce folate levels and fat-soluble vitamins A, D, E, and K. To prevent related complications, your vet may recommend regular vitamin B12 injections every few weeks as well as oral folate supplements.
Supplementation aids in keeping your dog’s immune system strong and supports overall health during EPI management. Periodic blood tests help monitor vitamin levels and adjust supplementation accordingly.
Although dietary fat intake is generally reduced, fat remains essential for skin health and vitamin absorption. Medium chain triglycerides (MCTs) like those found in unrefined coconut oil are more easily absorbed by dogs with EPI and serve as a valuable energy source. Omega-3 fatty acids sourced from fish oils also support inflammation reduction and coat quality.
Lifelong vigilance in feeding and medication administration are vital. Avoid giving treats or scraps not approved by your vet, as even small changes can upset the delicate digestive balance your dog needs.
Regular vet check-ups are necessary to monitor weight, adjust enzyme dosages, and check for any emerging nutritional issues. With consistent care and a personalised feeding plan, dogs with EPI can go on to lead happy, active lives.
When working with your vet, consider asking:
Feeding a dog with EPI is a careful balancing act of choosing the right low-fat, low-fibre diet rich in quality protein, combined with essential enzyme supplementation and vitamin support. The journey requires teamwork between you and your vet, with patient observation and adjustments along the way. With dedication, your dog can enjoy a good quality of life despite this challenging condition.