Haemorrhagic Diathesis DNA Testing for German Shepherds

German shepherds are large, imposing and handsome dogs, widely recognised and loved across the UK. They rank as one of the top 10 most popular dog breeds in the country.

Beyond companionship, German shepherds have a rich history as working dogs, excelling in guarding livestock, police, military, and detection roles due to their intelligence, endurance and versatility.

This breed often displays caution around strangers but bonds deeply with their trusted owners. Their high energy and intelligence thrive on both mental and physical challenges, making them highly trainable and devoted pets.

However, selective breeding has led to inherited health concerns in the breed’s modern population. One serious but less common condition is haemorrhagic diathesis, a bleeding disorder.

Haemorrhagic diathesis, also called bleeding diathesis, is a hereditary condition caused by a specific gene mutation affecting the blood’s ability to clot. Dogs with this disorder are prone to excessive bleeding, bruising easily and experiencing delayed or impaired wound healing. In severe cases, the condition can be fatal.

Fortunately, advanced DNA testing is available in the UK, allowing breeders to identify carriers and affected individuals. This helps plan mating pairs responsibly to prevent passing the disorder to puppies.

What is haemorrhagic diathesis in German shepherds?

This inherited bleeding disorder prevents normal blood clotting due to defective clotting factors, such as Factor VIII deficiency, often classified as a form of haemophilia A. It follows an X-linked recessive pattern, so males are more commonly affected, and females can be carriers even if symptom-free.

Symptoms include unusual susceptibility to bruising and bleeding from minor injuries, prolonged bleeding during wounds or surgery, slow healing, and sometimes spontaneous bleeding episodes without clear cause.

This condition cannot be cured, but understanding its genetic basis allows breeders to avoid producing affected pups.

How is DNA testing for haemorrhagic diathesis done?

DNA testing involves taking a sample, usually a cheek swab or blood sample, which is sent to authorised veterinary laboratories that specialise in genetic testing of dogs. These labs use modern techniques like Next Generation Sequencing to detect mutations linked to haemorrhagic diathesis.

The test results will categorise your German shepherd as clear (no mutation), carrier (heterozygous for the gene), or affected (shows mutation and symptoms).

Knowing these results is crucial for making informed and ethical breeding decisions.

Responsible breeding practices to prevent haemorrhagic diathesis

• Always test both breeding dogs for haemorrhagic diathesis before mating.
• Avoid mating two carriers or affected dogs to prevent affected offspring.
• Prefer breeding carriers only to clear dogs to maintain genetic diversity while reducing risk.
• Keep detailed health records and pedigree information to track hereditary conditions.
• Consult veterinary geneticists or recognised breed clubs for guidance on breeding decisions.
• Promote excellent health and care standards for breeding dogs and their puppies.

By following these recommendations, breeders can help reduce the prevalence of haemorrhagic diathesis and improve the overall health of the German shepherd breed.

Why is testing important for German shepherd owners and breeders?

Testing for haemorrhagic diathesis not only protects individual dogs from severe health risks but also supports responsible breeding programmes. It reduces the risk of producing affected puppies, ensuring healthier future generations.

Early awareness allows owners to manage any unexpected bleeding risks and seek vet care promptly.

Responsible breeding with genetic testing is a key step towards preserving the breed’s health and ensuring vibrant, long-lived companions for families across the UK.