Hereditary thrombopathia is an inherited genetic disorder affecting Basset Hound puppies and other breeds, causing abnormal bleeding due to impaired platelet function. This autosomal recessive condition means that a dog must inherit a mutated gene from both parents to show symptoms. Dogs carrying only one copy of the gene are asymptomatic carriers but can pass the disorder on to their offspring. Responsible breeding practices are essential, and affected dogs should never be used for breeding to prevent transmission.
Hereditary thrombopathia has been identified primarily in these breeds:
The disorder affects platelet function, preventing blood from clotting properly. Platelets fail to aggregate and adhere as they should, leading to excessive bleeding, even from minor injuries. This malfunction is due to specific defects in platelet glycoproteins crucial for clotting processes.
The symptoms of thrombopathia resemble other clotting disorders, making diagnosis a challenge. Common clinical signs include:
Blood counts and clotting factor levels in affected dogs are often normal, so standard blood tests may not detect the disorder. Definitive diagnosis requires specialised platelet function tests, usually performed by veterinary specialists. Genetic testing is also available to identify carriers and affected dogs, providing vital information for breeding management.
While there is no cure for hereditary thrombopathia, careful management significantly improves quality of life. Key strategies include:
Effective communication with your vet and regular health checks are essential to manage risks and maintain your dog's wellbeing.
Preventing the spread of thrombopathia is only possible by ensuring that affected dogs are not bred. All dogs intended for breeding should undergo genetic testing to determine their status:
Spaying or neutering dogs diagnosed with thrombopathia is advised to prevent passing the condition to puppies. Breeders should prioritise health screening and genetic counselling to support the health of future generations.
Hereditary thrombopathia is a serious genetic disorder affecting blood clotting in certain dog breeds, particularly Basset Hounds and Finnish Spitz. Early diagnosis through specialised testing and effective management can greatly reduce health risks. Responsible breeding practices including genetic testing and removal of affected dogs from breeding programs are critical to prevent the disorder's spread. If you think your dog may show bleeding-related symptoms, seek veterinary advice promptly to ensure appropriate care and support.