Macrothrombocytopenia (MTC-R) DNA Testing for Norfolk Terriers

Hereditary macrothrombocytopenia (MTC-R) is a condition in which platelets are abnormally large and produced in reduced numbers. In Norfolk Terriers, this condition is relatively common. This article explains how genetic testing can help manage this disease in Norfolk Terriers and how such testing benefits the breed.

Disclaimer: Our content is the result of veterinary knowledge, professional experience, and thorough research. Whilst we strive to be accurate and up to date, it does not substitute professional veterinary advice. Always consult a vet for your pet's specific needs.

MTC-R in Norfolk Terriers

MTC-R is a hereditary condition that primarily affects Norfolk Terriers. Dogs with this condition have platelets that are much larger than normal and present in lower numbers. Although affected dogs may not display obvious symptoms, the condition can complicate routine health assessments and, on rare occasions, may lead to serious health problems.

Diagnosing MTC-R

Diagnosis of MTC-R typically involves a full blood count (FBC) to assess platelet size and number. However, since dogs with MTC-R may have platelet counts that appear normal on some automated blood analysers, a manual examination of a blood smear may be necessary for an accurate diagnosis.

Genetic Testing for MTC-R

Genetic testing for MTC-R can identify whether a dog is a carrier of or is affected by the condition. This test is particularly useful for breeders who wish to reduce the prevalence of MTC-R within the breed.

How Genetic Testing Is Carried Out

Genetic testing for MTC-R is performed using a blood sample or cheek swab from the dog. The sample is sent to a laboratory that analyses the dog's DNA to look for the genetic mutation associated with MTC-R.

Benefits of Genetic Testing

Genetic testing for MTC-R offers several benefits. It can help breeders make more informed breeding decisions, reducing the prevalence of the condition in the breed over time. It can also help owners and vets better understand their dog's health status and plan appropriate care.

Summary

Genetic testing for MTC-R in Norfolk Terriers is a valuable tool for breeders and owners alike. If you have a Norfolk Terrier or are considering breeding, speak to your vet about this test and how it may benefit your dog and the breed as a whole.