The English setter is a native British breed with a rich history dating back to the 1400s. Despite its heritage, the breed is relatively rare in the UK; in 2018, only 22 English setters were advertised on Pets4Homes, making it 132nd in popularity among over 240 breeds. This limited gene pool means hereditary health issues are a particular concern, as they can spread more easily without careful breeding practices.
Responsible breeders and owners increasingly rely on DNA testing to identify hereditary conditions and protect the breed's future health. The Kennel Club regularly updates its recommendations and introduced two new advisory DNA testing schemes for English setters in 2019:
Progressive retinal atrophy is a serious eye condition that causes gradual, irreversible blindness in affected dogs. Although not painful, the progressive loss of sight significantly affects a dog's quality of life and care requirements. Several genetic variants of PRA exist and breed-specific testing is vital. For English setters, the relevant variant tested is PRA-rcd4, helping breeders avoid passing this debilitating condition to puppies.
NCL is an inherited disorder causing progressive degeneration of the nervous system. Its symptoms can include epilepsy, dementia, and vision loss, varying in onset and severity. Affected dogs face a challenging quality of life, making early DNA testing critical to prevent breeding affected or carrier dogs.
Currently, both PRA-rcd4 and NCL DNA tests for English setters are advisory, not mandatory. The Kennel Club and the English Setter breed health coordinator recommend these tests to encourage responsible breeding. However, they have not made them compulsory, even for Kennel Club Assured Breeders, who often undertake specific health screenings to promote breed welfare.
The testing process is simple and non-invasive. Owners and breeders can visit a vet to obtain a buccal swab or blood sample, which is sent to an approved laboratory for analysis. Clear results can be recorded in the breed health database, and certificates issued upon presentation of the dog's Kennel Club registration paperwork.
As of 2025, The Kennel Club's focus remains on protecting breeds from harmful genetic mutations, especially through controls on imports. There are no newly mandated or updated DNA testing schemes added specifically for English setters this year. Breeders are encouraged to continue following existing health protocols and DNA testing recommendations.
For additional health screening, the English Setter Association of America highlights other important tests, such as BAER hearing testing to detect inherited deafness, which while recommended, is not mandatory under The Kennel Club’s current guidelines.
Staying informed through breed clubs and The Kennel Club will help ensure breeders and owners uphold the health and welfare of this cherished British breed.
With the breed's limited population size, DNA testing plays a vital role in reducing the incidence of hereditary diseases. It helps breeders make informed decisions, avoiding mating carrier dogs that could produce affected puppies.
This responsible approach enhances the overall welfare of the breed and contributes to the longevity and quality of life for English setter dogs in the UK and beyond.
For those interested in finding or finding a reputable English setter puppy, look for breeders who prioritise comprehensive health testing and adhere to Kennel Club guidelines.